Biomarker Abbreviation:

also know as v-raf murine sarcoma viral oncogene homolog B1 - a proto-oncogene in the RAF/MIL family of molecules active in MAP/ERK cell signaling, promotes cell multiplication and growth. Cancers that may benefit from testing for this biomarker: colon, skin (melanoma), lung (adenocarcinoma), thyroid (papillary thyroid carcinoma), nervous system (pleomorphic xanthoastrocytomas with and without anaplasia)

Cancer Correlations:
Colorectal, Lung, Nervous System, Skin, Thyroid
Treatment Correlations:

cetuximab (Erbitux®), panitumumab (Vectibix®), vemurafenib (Zelboraf®)