c-MET

Biomarker Abbreviation:

c-MET

Definition:

also known as mesenchymal epithelial transition factor (MET) or hepatocyte growth factor receptor (HGFR) - a proto-oncogene active in cell signaling, c-MET promotes cancer cell growth and multiplication. Cancers that may benefit from testing for this biomarker: lung (non-small cell), ovarian

Cancer Correlations:

Lung, Ovarian

Treatment Correlations:

erlotinib (Tarceva®), gefitinib (Iressa®)