EGFR secondary mutation (T790 M)

Biomarker Abbreviation:
EGFR secondary mutation (T790 M)

A mutation of the EGFR gene associated with acquired resistance to certain treatments. Cancers that may benefit from testing for this biomarker: lung (non-small cell), colorectal, head and neck

Cancer Correlations:
Colorectal, Head & Neck, Lung
Treatment Correlations:

resistance to erlotinib (Tarceva®), gefitinib (Iressa®)