EGFR
Biomarker Abbreviation:
EGFR
Definition:
epidermal growth factor receptor, also known as ErbB-1 or HER1 - a receptor tyrosine kinase active in cell signaling, promotes cell growth and multiplication. Cancers that may benefit from testing for this biomarker: lung (non-small cell)
Cancer Correlations:
Lung
Treatment Correlations:
cetuximab (Erbitux®), erlotinib (Tarceva®), gefitinib (Iressa®), panitumumab (Vectibix®)