ERCC1

Biomarker Abbreviation:
ERCC1
Definition:

excision repair cross-complementation group 1 - an enzyme active in DNA repair and therefore a sign of resistance to treatments that work by disrupting tumor DNA. Cancers that may benefit from testing for this biomarker: lung (non-small cell and small cell), gastric, ovarian, colorectal, bladder

Cancer Correlations:
Bladder, Colorectal, Gastric, Lung, Ovarian
Treatment Correlations:

resistance to cisplatin (PlatinolĀ®), carboplatin (ParaplatinĀ®), oxaliplatin (EloxatinĀ®)