KRAS

Kirsten rat sarcoma viral oncogene homolog - a proto-oncogene of the Kirsten murine sarcoma virus, active in cell signaling in the EGFR pathway, promotes cell growth and multiplication. Cancers that may benefit from testing for this biomarker: lung (non-small cell), colon, pancreatic

cetuximab (Erbitux®), erlotinib (Tarceva®), gefitinib (Iressa®), panitumumab (Vectibix®)