Biomarker Abbreviation:

human epidermal growth factor receptor 2, also known as HER2/neu or ErbB-2 - a receptor tyrosine kinase active in cell signaling, promotes cell growth and multiplication. Cancers that may benefit from testing for this biomarker: breast, gastroesophageal, gastric, ovarian, colorectal.

Cancer Correlations:
Breast, Colorectal, Gastric, Ovarian
Treatment Correlations:

lapatinib (Tykerb®), trastuzumab (Herceptin®), doxorubicin (Adriamycin®, Rubex®), liposomal doxorubicin (Caelyx®, Myocet®), epirubicin (Ellence®)